Kcne4 deletion sex- and age-specifically impairs cardiac repolarization in mice

Myocardial repolarization capacity varies with sex, age, and pathology; the molecular basis for this variation is incompletely understood. Here, we show that the transcript for KCNE4, a voltage-gated potassium (K(v)) channel β subunit associated with human atrial fibrillation, was 8-fold more highly...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FASEB J
Prif Awduron: Crump, Shawn M., Hu, Zhaoyang, Kant, Ritu, Levy, Daniel I., Goldstein, Steve A. N., Abbott, Geoffrey W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Federation of American Societies for Experimental Biology 2016
Pynciau:
Research Communication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684512/
https://ncbi.nlm.nih.gov/pubmed/26399785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-278754
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