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In Vivo Evaluation of Matrix Metalloproteinase Responsive Silk-Elastinlike Protein Polymers for Cancer Gene Therapy

Silk-elastinlike protein polymers (SELPs) have been effectively used as controlled release matrices for the delivery of viruses for cancer gene therapy in preclinical models. However, the degradability of these polymers needs to be tuned for improved localized intratumoral gene delivery. Using recom...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Price, Robert, Poursaid, Azadeh, Cappello, Joseph, Ghandehari, Hamidreza
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684501/
https://ncbi.nlm.nih.gov/pubmed/26095079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.06.022
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