Pre-treatment protoporphyrin IX concentration in actinic keratosis lesions may be a predictive biomarker of response to aminolevulinic-acid based photodynamic therapy

BACKGROUND: Although Aminolevulinic Acid (ALA)-induced protoporphyrin IX (PpIX) photodynamic therapy (PDT) is an effective FDA-approved therapy for actinic keratosis (AK), a substantial fraction of patients (up to 25%) do not respond to treatment. This study examined the feasibility of using pre-tre...

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Udgivet i:Photodiagnosis Photodyn Ther
Main Authors: Kanick, SC, Davis, SC, Zhao, Y, Sheehan, KL, Hasan, T, Maytin, EV, Pogue, BW, Chapman, MS
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684466/
https://ncbi.nlm.nih.gov/pubmed/26480810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pdpdt.2015.10.006
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