Mesenchymal stem cells engineered to express selectin ligands and IL-10 exert enhanced therapeutic efficacy in murine experimental autoimmune encephalomyelitis

Systemic administration of mesenchymal stem cells (MSCs) affords the potential to ameliorate the symptoms of Multiple Sclerosis (MS) in both preclinical and clinical studies. However, the efficacy of MSC-based therapy for MS likely depends on the number of cells that home to inflamed tissues and on...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Liao, Wenbin, Pham, Victor, Liu, Linan, Riazifar, Milad, Pone, Egest J, Zhang, Shirley Xian, Ma, Fengxia, Lu, Mengrou, Walsh, Craig M., Zhao, Weian
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684451/
https://ncbi.nlm.nih.gov/pubmed/26584349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.11.005
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