A Cytomegalovirus DNA Vaccine Induces Antibodies that Block Viral Entry into Fibroblasts and Epithelial Cells

A vaccine to prevent congenital cytomegalovirus (CMV) infections is a national priority. Investigational vaccines have targeted the viral glycoprotein B (gB) as an inducer of neutralizing antibodies and phosphoprotein 65 (pp65) as an inducer of cytotoxic T cells. Antibodies to gB neutralize CMV entr...

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Udgivet i:Vaccine
Main Authors: McVoy, Michael A., Lee, Ronzo, Saccoccio, Frances M., Hartikka, Jukka, Smith, Larry R., Mahajan, Rohit, Ben Wang, Jian, Cui, Xiaohong, Adler, Stuart P.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684450/
https://ncbi.nlm.nih.gov/pubmed/26597035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.10.078
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