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Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges

In the infarcted myocardium, necrotic cardiomyocytes release danger signals, activating an intense inflammatory response. Inflammatory pathways play a crucial role in regulation of a wide range of cellular processes involved in injury, repair and remodeling of the infarcted heart. Pro-inflammatory c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Transl Res
Hauptverfasser: Saxena, Amit, Russo, Ilaria, Frangogiannis, Nikolaos G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684426/
https://ncbi.nlm.nih.gov/pubmed/26241027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2015.07.002
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