Establishment of an Animal Model of Bisphosphonate-Related Osteonecrosis of the Jaws in Spontaneously Diabetic Torii Rats

BACKGROUND: We evaluated the side effects of bisphosphonate (BP) on tooth extraction socket healing in spontaneously diabetic Torii (SDT) rats, an established model of non-obese type 2 diabetes mellitus, to develop an animal model of BP-related osteonecrosis of the jaws (BRONJ). MATERIALS AND METHOD...

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Publicat a:PLoS One
Autors principals: Takaoka, Kazuki, Yamamura, Michiyo, Nishioka, Toshihiro, Abe, Tetsuya, Tamaoka, Joji, Segawa, Emi, Shinohara, Masami, Ueda, Haruyasu, Kishimoto, Hiromitsu, Urade, Masahiro
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684366/
https://ncbi.nlm.nih.gov/pubmed/26659123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144355
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