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Branched-Chain Aminotransferases Control TORC1 Signaling in Saccharomyces cerevisiae
The conserved target of rapamycin complex 1 (TORC1) integrates nutrient signals to orchestrate cell growth and proliferation. Leucine availability is conveyed to control TORC1 activity via the leu-tRNA synthetase/EGOC-GTPase module in yeast and mammals, but the mechanisms sensing leucine remain only...
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| 出版年: | PLoS Genet |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4684349/ https://ncbi.nlm.nih.gov/pubmed/26659116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005714 |
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