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Branched-Chain Aminotransferases Control TORC1 Signaling in Saccharomyces cerevisiae
The conserved target of rapamycin complex 1 (TORC1) integrates nutrient signals to orchestrate cell growth and proliferation. Leucine availability is conveyed to control TORC1 activity via the leu-tRNA synthetase/EGOC-GTPase module in yeast and mammals, but the mechanisms sensing leucine remain only...
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| Publicado no: | PLoS Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4684349/ https://ncbi.nlm.nih.gov/pubmed/26659116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005714 |
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