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Constraint methods that accelerate free-energy simulations of biomolecules

Atomistic molecular dynamics simulations of biomolecules are critical for generating narratives about biological mechanisms. The power of atomistic simulations is that these are physics-based methods that satisfy Boltzmann’s law, so they can be used to compute populations, dynamics, and mechanisms....

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Dades bibliogràfiques
Publicat a:J Chem Phys
Autors principals: Perez, Alberto, MacCallum, Justin L., Coutsias, Evangelos A., Dill, Ken A.
Format: Artigo
Idioma:Inglês
Publicat: AIP Publishing LLC 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684272/
https://ncbi.nlm.nih.gov/pubmed/26723628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4936911
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