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Light Induces Ultrastructural Changes in Rod Outer and Inner Segments, Including Autophagy, in a Transgenic Xenopus laevis P23H Rhodopsin Model of Retinitis Pigmentosa

PURPOSE: We previously reported a transgenic Xenopus laevis model of retinitis pigmentosa in which tadpoles express the bovine form of P23H rhodopsin (bP23H) in rod photoreceptors. In this model, retinal degeneration was dependent on light exposure. Here, we investigated ultrastructural changes that...

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Bibliografski detalji
Izdano u:Invest Ophthalmol Vis Sci
Glavni autori: Bogéa, Tami H., Wen, Runxia H., Moritz, Orson L.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684193/
https://ncbi.nlm.nih.gov/pubmed/26720441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16799
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