Consistent gene expression profiles in MexTAg transgenic mouse and wild type mouse asbestos-induced mesothelioma

BACKGROUND: The MexTAg transgenic mouse model of mesothelioma replicates many aspects of human mesothelioma, including induction by asbestos, pathogenicity and response to cytotoxic chemotherapy, despite high levels of the SV40 large T Antigen (TAg) in the mesothelial compartment. This model enables...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Robinson, Cleo, Dick, Ian M., Wise, Michael J., Holloway, Andrew, Diyagama, Dileepa, Robinson, Bruce W. S., Creaney, Jenette, Lake, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683914/
https://ncbi.nlm.nih.gov/pubmed/26680231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1953-y
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