High EGFR protein expression and exon 9 PIK3CA mutations are independent prognostic factors in triple negative breast cancers

BACKGROUND: Triple negative breast cancers (TNBC) are a more aggressive subset of breast cancer. A better understanding of its biology could allow the rational development of targeted therapies. METHODS: We extensively analyzed the EGFR/PI3K/PTEN axis in a large, homogeneous population of TNBC to he...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Jacot, William, Mollevi, Caroline, Fina, Frédéric, Lopez-Crapez, Evelyne, Martin, Pierre-Marie, Colombo, Pierre-Emmanuel, Bibeau, Frédéric, Romieu, Gilles, Lamy, Pierre-Jean
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683760/
https://ncbi.nlm.nih.gov/pubmed/26680641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1977-3
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