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Predicting target proteins for drug candidate compounds based on drug-induced gene expression data in a chemical structure-independent manner
BACKGROUND: Phenotype-based high-throughput screening is a useful technique for identifying drug candidate compounds that have a desired phenotype. However, the molecular mechanisms of the hit compounds remain unknown, and substantial effort is required to identify the target proteins associated wit...
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| Vydáno v: | BMC Med Genomics |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4683716/ https://ncbi.nlm.nih.gov/pubmed/26684652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-015-0158-1 |
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