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Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration

Directed cell migration requires dynamical control of the protein complex within focal adhesions (FAs) and this control is regulated by signaling events involving tyrosine phosphorylation. We screened the SH2 domains present in tyrosine-specific kinases and phosphatases found within FAs, including S...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Wu, Jui-Chung, Chen, Yu-Chen, Kuo, Chih-Ting, Wenshin Yu, Helen, Chen, Yin-Quan, Chiou, Arthur, Kuo, Jean-Cheng
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683442/
https://ncbi.nlm.nih.gov/pubmed/26681405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18476
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