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CCR 20th Anniversary Commentary: MAPK/ERK Pathway Inhibition in Melanoma–Kinase Inhibition Redux

In the January 15, 2012, issue of Clinical Cancer Research, Kirkwood and colleagues published a study comparing the MEK inhibitor selumetinib to temozolomide in unselected metastatic melanoma. Although selumetinib did not improve survival or response, most responders had BRAF activating mutations, a...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Davar, Diwakar, Kirkwood, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683414/
https://ncbi.nlm.nih.gov/pubmed/26672083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-3132
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