Group B Streptococcus evades host immunity by degrading hyaluronan

In response to tissue injury, hyaluronan (HA) polymers are cleaved by host hyaluronidases generating small fragments that ligate Toll-Like Receptors to elicit inflammatory responses. Pathogenic bacteria such as Group B Streptococci (GBS) express and secrete hyaluronidases as a mechanism for tissue i...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Kolar, Stacey L., Kyme, Pierre, Tseng, Ching Wen, Soliman, Antoine, Kaplan, Amber, Liang, Jiurong, Nizet, Victor, Jiang, Dianhua, Murali, Ramachandran, Arditi, Moshe, Underhill, David M., Liu, George Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683412/
https://ncbi.nlm.nih.gov/pubmed/26651945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.11.001
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