Sildenafil reduces signs of oxidative stress in pulmonary arterial hypertension: Evaluation by fatty acid composition, level of hydroxynonenal and heart rate variability

Pulmonary arterial hypertension (PAH) is a rare multifactorial disease with an unfavorable prognosis. Sildenafil therapy can improve functional capacity and pulmonary hemodynamics in PAH patients. Nowadays, it is increasingly recognized that the effects of sildenafil are pleiotropic and may also inv...

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Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Semen, Khrystyna, Yelisyeyeva, Olha, Jarocka-Karpowicz, Iwona, Kaminskyy, Danylo, Solovey, Lyubomyr, Skrzydlewska, Elzbieta, Yavorskyi, Ostap
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683386/
https://ncbi.nlm.nih.gov/pubmed/26654977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.11.009
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