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N-helix and Cysteines Inter-regulate Human Mitochondrial VDAC-2 Function and Biochemistry
Human voltage-dependent anion channel-2 (hVDAC-2) functions primarily as the crucial anti-apoptotic protein in the outer mitochondrial membrane, and additionally as a gated bidirectional metabolite transporter. The N-terminal helix (NTH), involved in voltage sensing, bears an additional 11-residue e...
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| Published in: | J Biol Chem |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4683249/ https://ncbi.nlm.nih.gov/pubmed/26487717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.693978 |
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