Evidence supporting a critical contribution of intrinsically disordered regions to the biochemical behavior of full-length human HP1γ

HP1γ, a non-histone chromatin protein, has elicited significant attention because of its role in gene silencing, elongation, splicing, DNA repair, cell growth, differentiation, and many other cancer-associated processes, including therapy resistance. These characteristics make it an ideal target for...

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Model
Hauptverfasser: Velez, Gabriel, Lin, Marisa, Christensen, Trace, Faubion, William A., Lomberk, Gwen, Urrutia, Raul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2015
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683166/
https://ncbi.nlm.nih.gov/pubmed/26680990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-015-2874-z
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