Adenovirus Specific Pre-Immunity Induced by Natural Route of Infection Does Not Impair Transduction by Adenoviral Vaccine Vectors in Mice

Recombinant human adenovirus serotype 5 (HAd5V) vectors are gold standards of T-cell immunogenicity as they efficiently induce also humoral responses to exogenous antigens, in particular when used in prime-boost protocols. Some investigators have shown that pre-existing immunity to adenoviruses inte...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: de Andrade Pereira, Bruna, E. Maduro Bouillet, Leoneide, Dorigo, Natalia A., Fraefel, Cornel, Bruna-Romero, Oscar
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682971/
https://ncbi.nlm.nih.gov/pubmed/26679149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145260
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