Increased Protease-Activated Receptor-2 (PAR-2) Expression on CD14(++)CD16(+) Peripheral Blood Monocytes of Patients with Severe Asthma

BACKGROUND: Protease-Activated Receptor-2 (PAR-2), a G protein coupled receptor activated by serine proteases, is widely expressed in humans and is involved in inflammation. PAR-2 activation in the airways plays an important role in the development of allergic airway inflammation. PAR-2 expression i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shrestha Palikhe, Nami, Nahirney, Drew, Laratta, Cheryl, Gandhi, Vivek Dipak, Vethanayagam, Dilini, Bhutani, Mohit, Mayers, Irvin, Cameron, Lisa, Vliagoftis, Harissios
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682828/
https://ncbi.nlm.nih.gov/pubmed/26658828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144500
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