Indomethacin Prevents the Progression of Thoracic Aortic Aneurysm in Marfan Syndrome Mice

Background: Marfan syndrome (MFS), an inherited disorder of connective tissue characterized by abnormalities in the skeletal, ocular, and cardiovascular systems, is caused by mutations in the gene for fibrillin-1 (FBN1). The high mortality in untreated patients is primarily due to aneurysm and disse...

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Опубликовано в: :Aorta (Stamford)
Главные авторы: Guo, Gao, Ott, Claus-Eric, Grünhagen, Johannes, Muñoz-García, Begoña, Pletschacher, Angelika, Kallenbach, Klaus, von Kodolitsch, Yskert, Robinson, Peter N.
Формат: Artigo
Язык:Inglês
Опубликовано: Science International Corporation 2013
Предметы:
Original Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682693/
https://ncbi.nlm.nih.gov/pubmed/26798667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12945/j.aorta.2013.13.007
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