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Expression of mouse CD47 on human cancer cells profoundly increases tumor metastasis in murine models
BACKGROUND: Many commonly used xenograft tumor models do not spontaneously metastasize to distant organs following subcutaneous or orthotopic implantation, limiting their usefulness in preclinical studies. It is generally believed that natural killer cells are the key component of the innate immune...
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Publicado no: | BMC Cancer |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4682254/ https://ncbi.nlm.nih.gov/pubmed/26674012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1980-8 |
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