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Expression of mouse CD47 on human cancer cells profoundly increases tumor metastasis in murine models

BACKGROUND: Many commonly used xenograft tumor models do not spontaneously metastasize to distant organs following subcutaneous or orthotopic implantation, limiting their usefulness in preclinical studies. It is generally believed that natural killer cells are the key component of the innate immune...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Rivera, Armando, Fu, Xinping, Tao, Lihua, Zhang, Xiaoliu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682254/
https://ncbi.nlm.nih.gov/pubmed/26674012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1980-8
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