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HIV-1 CCR5 gene therapy will fail unless it is combined with a suicide gene

Highly active antiretroviral therapy (ART) has successfully turned Human immunodeficiency virus type 1 (HIV-1) from a deadly pathogen into a manageable chronic infection. ART is a lifelong therapy which is both expensive and toxic, and HIV can become resistant to it. An alternative to lifelong ART i...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Pandit, Aridaman, de Boer, Rob J.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682191/
https://ncbi.nlm.nih.gov/pubmed/26674113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18088
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