Measurement of the Nucleus Area and Nucleus/Cytoplasm and Mitochondria/Nucleus Ratios in Human Colon Tissues by Dual-Colour Two-Photon Microscopy Imaging

We developed two-photon (TP) probes for DNA (ABI-Nu), cytoplasm (Pyr-CT), and mitochondria (BF-MT). We found that ABI-Nu binds to AT in the minor groove, while ABI-Nu and BF-MT are effective for tracking in the cytoplasm and mitochondria, respectively. These probes showed very large effective two-ph...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Su Lim, Chang, Sun Kim, Eun, Yeon Kim, Ji, Taek Hong, Seung, Jai Chun, Hoon, Eun Kang, Dong, Rae Cho, Bong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682082/
https://ncbi.nlm.nih.gov/pubmed/26673743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18521
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