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Improved large-scale prediction of growth inhibition patterns using the NCI60 cancer cell line panel

Motivation: Recent large-scale omics initiatives have catalogued the somatic alterations of cancer cell line panels along with their pharmacological response to hundreds of compounds. In this study, we have explored these data to advance computational approaches that enable more effective and target...

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Vydáno v:Bioinformatics
Hlavní autoři: Cortés-Ciriano, Isidro, van Westen, Gerard J. P., Bouvier, Guillaume, Nilges, Michael, Overington, John P., Bender, Andreas, Malliavin, Thérèse E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681992/
https://ncbi.nlm.nih.gov/pubmed/26351271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv529
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