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RNF: a general framework to evaluate NGS read mappers

Motivation: Read simulators combined with alignment evaluation tools provide the most straightforward way to evaluate and compare mappers. Simulation of reads is accompanied by information about their positions in the source genome. This information is then used to evaluate alignments produced by th...

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Publié dans:Bioinformatics
Auteurs principaux: Břinda, Karel, Boeva, Valentina, Kucherov, Gregory
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681991/
https://ncbi.nlm.nih.gov/pubmed/26353839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv524
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