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SHAPE directed RNA folding

Summary: Chemical mapping experiments allow for nucleotide resolution assessment of RNA structure. We demonstrate that different strategies of integrating probing data with thermodynamics-based RNA secondary structure prediction algorithms can be implemented by means of soft constraints. This amount...

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Publicado en:Bioinformatics
Autores principales: Lorenz, Ronny, Luntzer, Dominik, Hofacker, Ivo L., Stadler, Peter F., Wolfinger, Michael T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681990/
https://ncbi.nlm.nih.gov/pubmed/26353838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv523
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