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Natural killer cells regulate T cell immune responses in primary biliary cirrhosis

The hallmark of primary biliary cirrhosis (PBC) is the presence of autoreactive T and B cell responses that target biliary epithelial cells (BEC). We have previously demonstrated that biliary cell cytotoxicity is dependent upon the initiation of innate immune responses followed by chronic adaptive a...

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Dettagli Bibliografici
Pubblicato in:Hepatology
Autori principali: Shimoda, Shinji, Hisamoto, Satomi, Harada, Kenichi, Iwasaka, Sho, Chong, Yong, Nakamura, Minoru, Bekki, Yuki, Yoshizumi, Tomoharu, Shirabe, Ken, Ikegami, Toru, Maehara, Yoshihiko, He, Xiao-Song, Gershwin, M Eric, Akashi, Koichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681684/
https://ncbi.nlm.nih.gov/pubmed/26264889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28122
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