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Nitric oxide regulates gene expression in cancers by controlling histone posttranslational modifications
Altered nitric oxide (•NO) metabolism underlies cancer pathology, but mechanisms explaining many •NO-associated phenotypes remain unclear. We have found that cellular exposure to •NO changes histone posttranslational modifications (PTMs) by directly inhibiting the catalytic activity of JmjC-domain c...
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| Опубликовано в: : | Cancer Res |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4681644/ https://ncbi.nlm.nih.gov/pubmed/26542213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1582 |
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