Glycogen Synthase Kinase 3 beta predicts survival in resected adenocarcinoma of the pancreas

PURPOSE: GSK3β is a protein kinase that can suppress a number of key oncoproteins. We have previously shown in preclinical models of pancreatic ductal adenocarcinoma (PDAC) that inhibition of GSK3β causes stabilization, nuclear translocation of β-catenin, poor differentiation, proliferation and resi...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Ben-Josef, Edgar, George, Asha, Regine, William F., Abrams, Ross, Morgan, Meredith, Thomas, Dafydd, Schaefer, Paul L., DiPetrillo, Thomas A., Fromm, Mitchel, Small, William, Narayan, Samir, Winter, Kathryn, Griffith, Kent A, Guha, Chandan, Williams, Terence M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681598/
https://ncbi.nlm.nih.gov/pubmed/26240274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0789
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