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Hereditary Spastic Paraplegia-Linked REEP1 Modulates ER-Mitochondria Contacts

OBJECTIVE: Mutations in receptor expression enhancing protein 1 (REEP1) are associated with hereditary spastic paraplegias (HSPs). Although axonal degeneration is thought to be a predominant feature in HSP, the role of REEP1 mutations in degeneration is largely unknown. Previous studies have implica...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Lim, Youngshin, Cho, Il-Taeg, Schoel, Leah J., Cho, Ginam, Golden, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681538/
https://ncbi.nlm.nih.gov/pubmed/26201691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24488
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