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Heterogeneous side chain conformation highlights a network of interactions implicated in hysteresis of the knotted protein, Minimal Tied Trefoil (MTT(Tm))
Hysteresis is a signature for a bistability in the native landscape of a protein with significant transition state barriers for the interconversion of stable species. Large global stability, as in GFP, contributes to the observation of this rare hysteretic phenomenon in folding. The signature for su...
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Publicado no: | J Phys Condens Matter |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4681393/ https://ncbi.nlm.nih.gov/pubmed/26291198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0953-8984/27/35/354108 |
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