Preventive Anti-CD2 Treatment does not Impair Parasite Control in a Murine Toxoplasmosis Model

Targeting human CD2 with the monoclonal antibody (mAb) CB.219 reduces intestinal inflammation in a colitis model where T cells carry human CD2. Here, we asked whether this mAb has adverse effects on infection control. Mice expressing human CD2 on T cells (huCD2tg) were orally infected with Toxoplasm...

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Bibliografske podrobnosti
izdano v:Eur J Microbiol Immunol (Bp)
Main Authors: Erben, U., Pawlowski, N. N., Heimesaat, M. M., Loddenkemper, C., Doerfel, K., Spieckermann, S., Siegmund, B., Kühl, A. A.
Format: Artigo
Jezik:Inglês
Izdano: Akadémiai Kiadó 2015
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681358/
https://ncbi.nlm.nih.gov/pubmed/26716019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1556/1886.2015.00040
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