Autophagy promotes apoptosis of mesenchymal stem cells under inflammatory microenvironment

BACKGROUND: Mesenchymal stem cells (MSCs) have been widely applied to treat various inflammatory diseases. Inflammatory cytokines can induce both apoptosis and autophagy in MSCs. However, whether autophagy plays a pro- or con-apoptosis effect on MSCs in an inflammatory microenvironment has not been...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Dang, Shipeng, Yu, Zhi-ming, Zhang, Chang-ying, Zheng, Jie, Li, Ku-lin, Wu, Ying, Qian, Ling-ling, Yang, Zhen-yu, Li, Xiao-rong, Zhang, Yanyun, Wang, Ru-xing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681177/
https://ncbi.nlm.nih.gov/pubmed/26670667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0245-4
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