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Cycling transcriptional networks optimize energy utilization on a genome scale

Genes expressing circadian RNA rhythms are enriched for metabolic pathways, however, the adaptive significance of cyclic gene expression remains unclear. We estimated the genome-wide synthetic and degradative cost of transcription and translation in three organisms and found that the cost of cycling...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Wang, Guang-Zhong, Hickey, Stephanie L., Shi, Lei, Huang, Hung-Chung, Nakashe, Prachi, Koike, Nobuya, Tu, Benjamin P., Takahashi, Joseph S., Konopka, Genevieve
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680985/
https://ncbi.nlm.nih.gov/pubmed/26655902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.043
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