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Expanding the Repertoire of Biomarkers for Alzheimer’s Disease: Targeted and Non-targeted Approaches

The first biofluid markers developed for Alzheimer’s disease (AD) used targeted approaches for discovery. These initial biomarkers were directed at key protein constituents of the hallmark brain lesions in AD. Biomarkers for plaques targeted the amyloid beta protein (Aβ) and for tangles, the microtu...

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Detalhes bibliográficos
Publicado no:Front Neurol
Autor principal: Galasko, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680926/
https://ncbi.nlm.nih.gov/pubmed/26733934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2015.00256
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