TP53 Mutational Analysis Enhances the Prognostic Accuracy of IHC4 and PAM50 Assays

IHC4 and PAM50 assays have been shown to provide additional prognostic information for patients with early breast cancer. We evaluated whether incorporating TP53 mutation analysis can further enhance their prognostic accuracy. We examined TP53 mutation and the IHC4 score in tumors of 605 patients di...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lin, Ching-Hung, Chen, I-Chiun, Huang, Chiun-Sheng, Hu, Fu-Chang, Kuo, Wen-Hung, Kuo, Kuan-Ting, Wang, Chung-Chieh, Wu, Pei-Fang, Chang, Dwan-Ying, Wang, Ming-Yang, Chang, Chin-Hao, Chen, Wei-Wu, Lu, Yen-Shen, Cheng, Ann-Lii
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680865/
https://ncbi.nlm.nih.gov/pubmed/26671300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17879
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