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The RZZ complex requires the N-terminus of KNL1 to mediate optimal Mad1 kinetochore localization in human cells
The spindle assembly checkpoint is a surveillance mechanism that blocks anaphase onset until all chromosomes are properly attached to microtubules of the mitotic spindle. Checkpoint activity requires kinetochore localization of Mad1/Mad2 to inhibit activation of the anaphase promoting complex/cyclos...
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| 發表在: | Open Biol |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Royal Society
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4680571/ https://ncbi.nlm.nih.gov/pubmed/26581576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150160 |
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