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Evolution of lineage-specific functions in ancient cis-regulatory modules

Morphological evolution is driven both by coding sequence variation and by changes in regulatory sequences. However, how cis-regulatory modules (CRMs) evolve to generate entirely novel expression domains is largely unknown. Here, we reconstruct the evolutionary history of a lens enhancer located wit...

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發表在:Open Biol
Main Authors: Pauls, Stefan, Goode, Debbie K., Petrone, Libero, Oliveri, Paola, Elgar, Greg
格式: Artigo
語言:Inglês
出版: The Royal Society 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680567/
https://ncbi.nlm.nih.gov/pubmed/26538567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150079
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