Amplification of chromosome 8q21-qter associated with the acquired paclitaxel resistance of nasopharyngeal caricinoma cells

Objective: to observe relationship between chromosome imbalance and taxol resistance in nasopharyngeal carcinoma (NPC). Methods: three taxol-resistant sub-lines were established through repeated exposure of escalating doses of paclitaxel to NPC cell lines (CNE-1, HNE-2 and 5-8F). The change of copy...

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Publicat a:Int J Clin Exp Pathol
Autors principals: Li, Wei, You, Yating, Zhang, Xiaowei, Song, Yexun, Xiang, Hong, Peng, Xiaowei, Qin, Jiangbo, Tan, Guolin
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680366/
https://ncbi.nlm.nih.gov/pubmed/26722421
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