Ganciclovir concentrations in the cerebral extracellular space after valganciclovir treatment; a case study

Nearly all glioblastomas (GBMs), brain tumours with very poor prognosis, are infected with human cytomegalovirus (CMV). The anti-CMV drug valganciclovir (VGCV) has shown promise as a treatment option for patients with GBM, but its penetration into the central nervous system (CNS) is unknown. Here we...

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Vydáno v:BMJ Case Rep
Hlavní autoři: Peredo, Inti, Helldén, Anders, Wolmer-Solberg, Nina, Pohanka, Anton, Stragliotto, Giuseppe, Rahbar, Afsar, Ståhle, Lars, Bellander, Bo-Michael, Söderberg-Nauclér, Cecilia
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680241/
https://ncbi.nlm.nih.gov/pubmed/26670887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr-2014-207694
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