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Chronic Glutamate Toxicity in Neurodegenerative Diseases—What is the Evidence?

Together with aspartate, glutamate is the major excitatory neurotransmitter in the brain. Glutamate binds and activates both ligand-gated ion channels (ionotropic glutamate receptors) and a class of G-protein coupled receptors (metabotropic glutamate receptors). Although the intracellular glutamate...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Lewerenz, Jan, Maher, Pamela
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679930/
https://ncbi.nlm.nih.gov/pubmed/26733784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00469
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