Reduced Responses of Submucous Neurons from Irritable Bowel Syndrome Patients to a Cocktail Containing Histamine, Serotonin, TNFα, and Tryptase (IBS-Cocktail)

Background and Aims: Malfunctions of enteric neurons are believed to play an important role in the pathophysiology of irritable bowel syndrome (IBS). Our aim was to investigate whether neuronal activity in biopsies from IBS patients is altered in comparison to healthy controls (HC). Methods: Activit...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Ostertag, Daniela, Buhner, Sabine, Michel, Klaus, Pehl, Christian, Kurjak, Manfred, Götzberger, Manuela, Schulte-Frohlinde, Ewert, Frieling, Thomas, Enck, Paul, Phillip, Josef, Schemann, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679876/
https://ncbi.nlm.nih.gov/pubmed/26733780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00465
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