Developmental Neurotoxicity of Tobacco Smoke Directed Toward Cholinergic and Serotonergic Systems: More Than Just Nicotine

Tobacco smoke contains thousands of compounds in addition to nicotine, a known neuroteratogen. We evaluated the developmental neurotoxicity of tobacco smoke extract (TSE) administered to pregnant rats starting preconception and continued through the second postnatal week. We simulated nicotine conce...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Slotkin, Theodore A., Skavicus, Samantha, Card, Jennifer, Stadler, Ashley, Levin, Edward D., Seidler, Frederic J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Developmental Exposure to Tobacco Smoke and Altered Neurotransmitter Function
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679867/
https://ncbi.nlm.nih.gov/pubmed/26085346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv123
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