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Guggulsterone induces apoptosis of human hepatocellular carcinoma cells through intrinsic mitochondrial pathway

AIM: To investigate the effects of guggulsterone on the proliferation and apoptosis of human hepatoma HepG2 cells in vitro and relevant mechanisms. METHODS: Human hepatocellular carcinoma HepG2 cells and normal human liver L-02 cells were treated with different concentrations of guggulsterone (5-100...

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Bibliographic Details
Published in:World J Gastroenterol
Main Authors: Shi, Juan-Juan, Jia, Xiao-Li, Li, Mei, Yang, Ning, Li, Ya-Ping, Zhang, Xin, Gao, Ning, Dang, Shuang-Suo
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679759/
https://ncbi.nlm.nih.gov/pubmed/26715810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i47.13277
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