Optogenetic Stimulation of Cholinergic Brainstem Neurons During Focal Limbic Seizures: Effects on Cortical Physiology

Focal temporal lobe seizures often cause impaired cortical function and loss of consciousness. Recent work suggests that the mechanism for depressed cortical function during focal seizures may depend on decreased subcortical cholinergic arousal, which leads to a sleep-like state of cortical slow-wav...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: Furman, Moran, Zhan, Qiong, McCafferty, Cian, Lerner, Benjamin A, Motelow, Joshua E, Meng, Jin, Ma, Chanthia, Buchanan, Gordon F, Witten, Ilana B, Deisseroth, Karl, Cardin, Jessica A, Blumenfeld, Hal
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679683/
https://ncbi.nlm.nih.gov/pubmed/26530287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13220
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