Partial Sleep Deprivation Activates the DNA Damage Response (DDR) and the Senescence-Associated Secretory Phenotype (SASP) in Aged Adult Humans

Age-related disease risk has been linked to short sleep duration and sleep disturbances; however, the specific molecular pathways linking sleep loss with diseases of aging are poorly defined. Key cellular events seen with aging, which are thought to contribute to disease, may be particularly sensiti...

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Udgivet i:Brain Behav Immun
Main Authors: Carroll, Judith E., Cole, Steven W., Seeman, Teresa E., Breen, Elizabeth C., Witarama, Tuff, Arevalo, Jesusa M.G., Ma, Jeffrey, Irwin, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679552/
https://ncbi.nlm.nih.gov/pubmed/26336034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2015.08.024
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