Whole Exome Sequence Analysis Implicates Rare Il17REL Variants In Familial And Sporadic Inflammatory Bowel Disease

BACKGROUND: Rare variants (<1%) likely contribute significantly to risk for common diseases such as inflammatory bowel disease (IBD) in specific patient subsets, such as those with high familiality. They are, however, extraordinarily challenging to identify. METHODS: To discover candidate rare va...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Sasaki, Mark M, Skol, Andrew D, Hungate, Eric A, Bao, Riyue, Huang, Lei, Kahn, Stacy A, Allan, James M, Brant, Steven R, McGovern, Dermot PB, Peter, Inga, Silverberg, Mark S, Cho, Judy H, Kirschner, Barbara S, Onel, Kenan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679526/
https://ncbi.nlm.nih.gov/pubmed/26480299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000610
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