Increased expression of the epithelial anion transporter Pendrin/SLC26A4 in nasal polyps of patients with Chronic Rhinosinusitis

BACKGROUND: Chronic rhinosinusitis (CRS) is a multifactorial disease of unknown etiology characterized by sinonasal inflammation, increased mucus production and defective mucociliary clearance. Pendrin, an epithelial anion transporter, is increased in asthma and chronic obstructive pulmonary disease...

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Pubblicato in:J Allergy Clin Immunol
Autori principali: Seshadri, Sudarshan, Lu, Xiang, Purkey, Matthew R., Homma, Tetsuya, Choi, Andrew Wonho, Carter, Roderick, Suh, Lydia, Norton, James, Harris, Kathleen E., Conley, David B., Kato, Atsushi, Avila, Pedro C., Czarnocka, Barbara, Kopp, Peter A, Peters, Anju T, Grammer, Leslie C, Chandra, Rakesh K., Tan, Bruce K., Liu, Zheng, Kern, Robert C., Schleimer, Robert P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679496/
https://ncbi.nlm.nih.gov/pubmed/26143180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.05.024
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